Pancreatic cancer often develops quietly, revealing itself only when it’s advanced. This stealthy nature makes awareness of its symptoms crucial for early detection. The pancreas, a vital organ hidden deep in your abdomen, plays dual roles in digestion and blood sugar regulation. When cancer strikes this important organ, the signs can be subtle but significant.
One of the most common red flags is unexplained weight loss. If you’re shedding pounds without trying, especially combined with appetite loss, it’s worth investigating. Yellowing of the skin and eyes (jaundice) occurs when a tumor blocks bile ducts, while persistent abdominal pain that radiates to the back may signal tumor growth. Digestive troubles like chronic indigestion or oily, foul-smelling stools can indicate the pancreas isn’t producing enough enzymes.

Other warning signs include sudden diabetes diagnosis in adults, changes in stool appearance, and unrelenting fatigue. Back pain that won’t quit, unexplained blood clots, and frequent nausea after small meals also make the list. While these symptoms can have many causes, their persistence warrants medical attention.
Risk factors like smoking, obesity, family history, and certain genetic conditions increase vulnerability. African Americans and Ashkenazi Jews face higher risks, as do people exposed to certain industrial chemicals. While prevention isn’t guaranteed, maintaining a healthy weight, avoiding tobacco, and eating balanced meals may lower your risk.